The immune system is known as CD8 + T cells that have the task to kill HIV-infected cells. For them to work properly required special ignition keys, transcription factors, to trigger defense. Now, researchers have found that two of the main ignition keys do not work as they would need to beat out the HIV virus.
- Just this ignition keys, so to speak, is important to educate the immune system, but we believe that the immune system trained wrong because it partially shuts down before the HIV virus has been eliminated, explains Marcus Buggert, biomedical scientists and researchers at the Karolinska Institute.
Would you think of how the defense can be put back on and continue to destroy the virus, it could lead to a cure of HIV and perhaps a vaccine.
No one knows the long term effects to go with the premium immunity as long as may be needed, but perhaps some who have HIV be prepared to take any risk, speculate, Marcus Buggert.
The finding may also have applications in, for example, cancer research, he believes.
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